Programmed longevity, youthspan, and juventology – lifespans and Healthspan

Volter Longo has some interesting new ideas regarding how we look at life expectancy, lifespan. He recommends thinking about spans in terms of youthspan (peak health 20-60) and Healthspan (oriented to disease free stage and the older phase (65-120).

check – Longo VD. Programmed longevity, youthspan, and juventology. Aging Cell. 2019;18:e12843. 

also check David Sinclair’s new book Lifespan: Why We Age―and Why We Don’t Have To — is a really great book! Highly recommended …. packed with information … some should be taken with a grain of salt or maybe with a Sirtuin activator like NMN 🙂




Earth BioGenome Project


[Lewin, H. A., Robinson, G. E., Kress, W. J., Baker, W. J., Coddington, J., Crandall, K. A., … & Goldstein, M. M. (2018). Earth BioGenome Project: Sequencing life for the future of life. Proceedings of the National Academy of Sciences, 115(17), 4325-4333.]

this should make one humble. …

We are only just beginning to understand the full majesty of life on Earth. Although 10–15 million eukaryotic species and perhaps trillions of bacterial and archaeal species adorn the Tree of Life, ∼2.3 mil- lion are actually known, and of those, fewer than 15,000, mostly microbes, have completed or partially sequenced genomes


Pretty Ambitious!  … and rather important!