Mediterranean diet and telomere length

Looking at

 

Conclusion In this large study, greater adherence to the Mediterranean diet was associated with longer telomeres. These results further support the benefits of adherence to the Mediterranean diet for promoting health and longevity.”

So,  that seems promising … the question….. can you ‘stick with the diet’?  Of course, there are other studies that provide other results.  How does one resolve the discrepancies?

Stat tuned … Ideas coming soon 🙂

 

in the meanwhile some people like these dish ideas

 

Towards an Open Research Knowledge Graph – One must chuckle

One must chuckle … I was looking at Towards an Open Research Knowledge Graph by
Sören Auer & Sanjeet Mann

It’s behind a paywall …

Can we please not use the phrase Open Anything unless its actually open and available without a paywall 🙂

 

 

 

Earth BioGenome Project

 

[Lewin, H. A., Robinson, G. E., Kress, W. J., Baker, W. J., Coddington, J., Crandall, K. A., … & Goldstein, M. M. (2018). Earth BioGenome Project: Sequencing life for the future of life. Proceedings of the National Academy of Sciences, 115(17), 4325-4333.]

this should make one humble. …

We are only just beginning to understand the full majesty of life on Earth. Although 10–15 million eukaryotic species and perhaps trillions of bacterial and archaeal species adorn the Tree of Life, ∼2.3 mil- lion are actually known, and of those, fewer than 15,000, mostly microbes, have completed or partially sequenced genomes

 

Pretty Ambitious!  … and rather important!

Carotenoids Database provides information on 1182 natural carotenoids 

The Carotenoids Database looks pretty cool!

According to the site it “currently provides information on 1182 natural carotenoids  in 700 source organisms..

Check it out here 

A recent review paper,  [Rodriguez-Concepcion, M., Avalos, J., Bonet, M. L., Boronat, A., Gomez-Gomez, L., Hornero-Mendez, D., … & Ribot, J. (2018). A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health. Progress in lipid research, 70, 62-93.]

states

Carotenoids are isoprenoid metabolites synthesized by all photosynthetic organisms (including plants, algae and cyanobacteria) and some non-photosynthetic archaea, bacteria, fungi and animals. In photosynthetic systems, carotenoids participate in light harvesting and they are essential for photoprotection

 

[AND]

In addition, carotenoids can be cleaved to produce compounds with roles as growth regulators, such as abscisic acid (ABA) and strigolactones, as well as bioactive molecules. Most animals (including humans) do not synthesize carotenoids de novo but take them in the diet and use them as essential precursors for the production of retinoids such as vitamin A. Additionally; carotenoids have been proposed to confer other health benefits whose discovery is spurring their use in functional food products.

 

This needs to be included in the Artificial Intelligence for Medicine Initiative

Bats are the longest-lived mammals for their size

I didn’t know that 🙂 apparently others do … cool!

Only 19 species of mammal are longer-lived than humans given their body size, and 18 of these species are bats

check this paper out.  [Foley, Nicole M., Graham M. Hughes, Zixia Huang, Michael Clarke, David Jebb, Conor V. Whelan, Eric J. Petit et al. “Growing old, yet staying young: The role of telomeres in bats’ exceptional longevity.” Science advances 4, no. 2 (2018): eaao0926.]

 

 

klotho and βklotho, were highly correlated with longevity

more later … if you really want the details .. look at

 

Li, Jun-Yan, Hsin-Yi Chen, Wen-Jie Dai, and Calvin Yu-Chian Chen. “Deep Learning to Investigate Longevity Drug.” Available at SSRN 3361157 (2019).

 

in any case, from the virtual experiment it looks like Antifebrile Dichroa, ArecaeSemen and Gelsemium sempervirens are part of the mystery.